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BChE-IN-17

Catalog No.GC71321

BChE-IN-17 (compound 6n) is a potent and selective BChE inhibitor with IC50s of 10.5 nM and 32.5 nM for eqBChE and hBChE, respectively.

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BChE-IN-17 Chemical Structure

Cas No.: 2425632-57-9

Size Price Stock Qty
5 mg
$140.00
In stock
10 mg
$221.00
In stock
25 mg
$441.00
In stock
50 mg
$707.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
BChE-IN-17 (compound 6n) is a potent and selective BChE inhibitor with IC50s of 10.5 nM and 32.5 nM for eqBChE and hBChE, respectively. BChE-IN-17 shows over 1000-fold selectivity to BChE against AChE. BChE-IN-17 shows low neurotoxicity and moderate neuroprotective effects.

References:
[1]. Tingkai Chen, et al. The structural modification and biological evaluation of tetrahydrothienopyridine derivatives as selective BChE inhibitors. Bioorg Med Chem Lett. 2023 Sep 1;93:129436.

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