Bis-PEG9-acid |
Catalog No.GC65801 |
Bis-PEG9-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG9-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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Cas No.: 1268488-70-5
Sample solution is provided at 25 µL, 10mM.
Bis-?PEG9-?acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-?PEG9-?acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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