BML283 (Synonyms: 1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-ylsulfonyl)-4-(4-methoxyphenylsulfonyl)piperazine) |
| Catalog No.GB40127 |
BML283 (562867-96-3) is a selective activator of the Tumor Specific M2 Isoform of Pyruvate Kinase (PKM2) - AC50 = 111nM. PKM2 activity is downregulated in most cancer cells leading to a decrease in catabolic metabolism and an increase in anabolic metabolism. BML283 is an important tool for studying the effects of PKM2 and cancer metabolism.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 562867-96-3
Sample solution is provided at 25 µL, 10mM.
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BML283 (562867-96-3) is a selective activator of the Tumor Specific M2 Isoform of Pyruvate Kinase (PKM2) - AC50 = 111nM. PKM2 activity is downregulated in most cancer cells leading to a decrease in catabolic metabolism and an increase in anabolic metabolism. BML283 is an important tool for studying the effects of PKM2 and cancer metabolism.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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