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Cyclocytidine HCl (Synonyms: Ancitabine hydrochloride, NSC 145668, 2,2′-O-Cyclocytidine hydrochloride)

Catalog No.GC17795

Ancitabine (hydrochloride) is an important antileukemia drugs.

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Cyclocytidine HCl Chemical Structure

Cas No.: 10212-25-6

Size Price Stock Qty
100mg
$38.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description of Cyclocytidine HCl

Ancitabine (hydrochloride) is an important antileukemia drugs.

References:
[1]. Z Rao, et al. Study on the Synthesis of Cytarabine Hydrochloride and its Intermediate Ancitabine Hydrochloride. Fine Chemical Intermediates, 2013

Chemical Properties of Cyclocytidine HCl

Cas No. 10212-25-6 SDF
Synonyms Ancitabine hydrochloride, NSC 145668, 2,2′-O-Cyclocytidine hydrochloride
Chemical Name 2-(hydroxymethyl)-6-imino-2,3,3a,9a-tetrahydrofuro[1,2][1,3]oxazolo[3,4-a]pyrimidin-3-ol;hydrochloride
Canonical SMILES C1=CN2C3C(C(C(O3)CO)O)OC2=NC1=N.Cl
Formula C9H12ClN3O4 M.Wt 261.66
Solubility DMF: Partially soluble,DMSO: Partially soluble,Ethanol: Partially soluble,PBS (pH 7.2): 10 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Cyclocytidine HCl

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1 mg 5 mg 10 mg
1 mM 3.8218 mL 19.1088 mL 38.2175 mL
5 mM 0.7644 mL 3.8218 mL 7.6435 mL
10 mM 0.3822 mL 1.9109 mL 3.8218 mL
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In vivo Formulation Calculator (Clear solution) of Cyclocytidine HCl

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Review for Cyclocytidine HCl

Average Rating: 5 ★★★★★ (Based on Reviews and 31 reference(s) in Google Scholar.)

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