D-Glucose-6-phosphate (sodium salt) (Synonyms: G6P, Sodium Glucose-6-Phosphate) |
| Catalog No.GC43434 |
D-Glucose-6-phosphate (sodium salt) is an essential component of glucose metabolism. It is formed in cells when glucose is phosphorylated by hexokinase (or glucokinase) or glucose-1-phosphate is converted by phosphoglucomutase, which is the first step in glycogen synthesis.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 54010-71-8
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
D-Glucose-6-phosphate (sodium salt) is an essential component of glucose metabolism. It is formed in cells when glucose is phosphorylated by hexokinase (or glucokinase) or glucose-1-phosphate is converted by phosphoglucomutase, which is the first step in glycogen synthesis [1]. D-Glucose 6-Phosphate is located at the starting point of two major metabolic pathways: glycolysis and the pentose phosphate pathway [2]. D-Glucose 6-Phosphate can be converted to glycogen or starch and stored in cells [3]. D-Glucose 6-Phosphate can be used as a substrate to measure the activity of recombinant mannitol-1-phosphatase (M1Pase) [4]. D-Glucose 6-Phosphate can be used as a substrate to measure the specificity of SapM protein [5]. This product is the sodium salt form of D-Glucose 6-Phosphate, with a molecular formula of C6H12NaO9P and a molecular weight of 282.12.
References:
[1]Jang W, Gomer R H. Exposure of cells to a cell number-counting factor decreases the activity of glucose-6-phosphatase to decrease intracellular glucose levels in Dictyostelium discoideum[J]. Eukaryotic cell, 2005, 4(1): 72-81.
[2]Litwack, Gerald .Chapter 6-Insulin and Sugars.Human Biochemistry. Academic Press.2018:131–160.
[3]Lal M A. Metabolism of storage carbohydrates[J]. Plant physiology, development and metabolism. Springer Nature, Singapore. Doi, 2018, 10: 978-981.
[4] Groisillier A, Tonon T. Determination of Recombinant Mannitol-1-phosphatase Activity from Ectocarpus sp[J]. Bio-protocol, 2016, 6(16): e1896-e1896.
[5]Fernandez-Soto P, Bruce A J E, Fielding A J, et al. Mechanism of catalysis and inhibition of Mycobacterium tuberculosis SapM, implications for the development of novel antivirulence drugs[J]. Scientific reports, 2019, 9(1): 10315.
| Cas No. | 54010-71-8 | SDF | |
| Synonyms | G6P, Sodium Glucose-6-Phosphate | ||
| Chemical Name | sodium ((2R,3S,4S,5R,6R)-3,4,5,6-tetrahydroxytetrahydro-2H-pyran-2-yl)methyl hydrogenphosphate | ||
| Canonical SMILES | O[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)COP(O)([O-])=O.[Na+] | ||
| Formula | C6H12NaO9P | M.Wt | 282.12 |
| Solubility | 10mg in PBS， pH 7.2 | Storage | Store at 2-8°C; sealed storage, away from moisture |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
||
| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 3.5446 mL | 17.723 mL | 35.4459 mL |
| 5 mM | 0.7089 mL | 3.5446 mL | 7.0892 mL |
| 10 mM | 0.3545 mL | 1.7723 mL | 3.5446 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 15 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *