D-(+)-Ribonic Acid γ-lactone (Synonyms: NSC 1031) |
Catalog No.GC91486 |
D-(+)-Ribonic acid γ-lactone is an oxidized derivative of ribose and a synthetic material.
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Cas No.: 5336-08-3
Sample solution is provided at 25 µL, 10mM.
D-(+)-Ribonic acid γ-lactone is an oxidized derivative of ribose and a synthetic material.[1] It has been used as a starting material in the synthesis of the ionophore antibiotic lasalocid , the natural products aristeromycin and (−)-neplanocin A , as well as an intermediate in the synthesis of ganglioside GM1 mimetic cholera toxin binder ligands.1,2,3
References:
[1].Ireland, R.E., Anderson, R.C., Badoud, R., et al.The total synthesis of ionophore antibiotics. A convergent synthesis of lasalocid A (X537A)J. Am Chem. Soc.105 (7)1988-2006(1983).
[2].Wolfe, M.S., Anderson, B.L., Borcherding, D.R., et al.Enantiospecific syntheses of aristeromycin and neplanocin AJ. Org. Chem.55(15)4712-4717(1990).
[3].Arosio, D., Vrasidas, I., Valentini, P., et al.Synthesis and cholera toxin binding properties of multivalent GM1 mimicsOrg. Biomol. Chem.2(14)2113-2124(2004).
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