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1,5-Anhydrosorbitol (Synonyms: 1,5-AG, 1,5-Anhydroglucitol, 1,5-Anhydro-D-sorbitol, 1,5-Anhydrosorbitol, 1-Deoxy-D-glucopyranose, 1-Deoxy-D-glucose, 1,5-D-Sorbitol)

Katalog-Nr.GC33801

1,5-Anhydrosorbitol ist ein Kurzzeitmarker fÜr die glykÄmische Kontrolle.

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1,5-Anhydrosorbitol Chemische Struktur

Cas No.: 154-58-5

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Sample solution is provided at 25 µL, 10mM.

Description of 1,5-Anhydrosorbitol

1,5-Anhydrosorbitol is a short-term marker for glycemic control.

1,5-Anhydrosorbitol can indicate that metabolite score marks individuals at higher risk for developing diabetes or insulin resistance and thereby coronary heart disease(CHD)[1].

[1]. Vaarhorst AA, et al. A metabolomic profile is associated with the risk of incident coronary heart disease. Am Heart J. 2014 Jul;168(1):45-52.e7.

Chemical Properties of 1,5-Anhydrosorbitol

Cas No. 154-58-5 SDF
Überlieferungen 1,5-AG, 1,5-Anhydroglucitol, 1,5-Anhydro-D-sorbitol, 1,5-Anhydrosorbitol, 1-Deoxy-D-glucopyranose, 1-Deoxy-D-glucose, 1,5-D-Sorbitol
Canonical SMILES OC[C@@H]1[C@@H](O)[C@H](O)[C@H](CO1)O
Formula C6H12O5 M.Wt 164.16
Löslichkeit DMF: 30 mg/ml,DMSO: 25 mg/ml,Ethanol: 2 mg/ml,PBS (pH 7.2): 10 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of 1,5-Anhydrosorbitol

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 6.0916 mL 30.4581 mL 60.9162 mL
5 mM 1.2183 mL 6.0916 mL 12.1832 mL
10 mM 0.6092 mL 3.0458 mL 6.0916 mL
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In vivo Formulation Calculator (Clear solution) of 1,5-Anhydrosorbitol

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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