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1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one

Katalog-Nr.GC71928

1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one ist ein potenter Nucleocapsid-N-Protein-Inhibitor, der aus Curcuma kwangsiensis isoliert werden kann.

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1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one Chemische Struktur

Cas No.: 149732-52-5

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1 mg
389,00 $
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one is a potent nucleocapsid (N) protein inhibitor can be isolated from Curcuma kwangsiensis. 1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one exhibits excellent antiviral activity against HCoV-OC43 and SARS-CoV-2,with EC50 values of 0.16 μM and 0.17 μM, respectively.

References:
[1]. Yang Liu, et al. 1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one inhibits SARS-CoV-2 by targeting the nucleocapsid protein. Acta Materia Medica. 2023. Vol. 2(3):270-280.

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