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&#181-Conotoxin-CnIIIC acetate

Katalog-Nr.GC72133

µ-Conotoxin-CnIIIC acetate, ein 22-Rückstandskonopeptid, ist ein starker Antagonist des spannungsgesteuerten NaV1.4-Natriumkanals mit einem IC50 von 1,3 nM, der an der neuromuskulären Kreuzung wirkt.

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µ-Conotoxin-CnIIIC acetate Chemische Struktur

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1 mg
45,00 $
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5 mg
135,00 $
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10 mg
216,00 $
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
µ-Conotoxin-CnIIIC acetate, a 22-residue conopeptide, is a potent antagonist of the voltage-gated NaV1.4 sodium channel with an IC50 of 1.3 nM acting at the neuromuscular junction. µ-Conotoxin-CnIIIC acetate has myorelaxant and analgesic effects.

References:
[1]. Del Río-Sancho S, et al. Cutaneous iontophoresis of μ-conotoxin CnIIIC-A potent NaV1.4 antagonist with analgesic, anaesthetic and myorelaxant properties. Int J Pharm. 2017 Feb 25;518(1-2):59-65.

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