5-Hydroxymethylcytosine (Synonyms: 5hmC) |
| Katalog-Nr.GC25021 |
5-Hydroxymethylcytosine (5hmC) is a naturally existing component in mammalian genomic DNA and is regarded as the sixth DNA base. 5-Hydroxymethylcytosine is an intermediate metabolite in active DNA demethylation. 5-Hydroxymethylcytosine is epigenetic marks known to affect global gene expression in mammals.
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Cas No.: 1123-95-1
Sample solution is provided at 25 µL, 10mM.
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5-Hydroxymethylcytosine (5hmC) is a naturally existing component in mammalian genomic DNA and is regarded as the sixth DNA base. 5-Hydroxymethylcytosine is an intermediate metabolite in active DNA demethylation. 5-Hydroxymethylcytosine is epigenetic marks known to affect global gene expression in mammals.
[1] Ke Fang, et al. Yi Chuan. 2016 Mar;38(3):206-16. [2] JesÚs Rafael RodrÍguez-Aguilera,, et al. Sci Rep. 2020 May 8;10(1):7822. [3] Wenshuai Li, et al. Cell Res. 2017 Oct;27(10):1243-1257.
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