AB21 hydrochloride |
| Katalog-Nr.GC71107 |
AB21 hydrochloride ist ein potenter und selektiver S1R-Antagonist mit Kis von 13, 102 nM für S1R und S2R.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 3026677-24-4
Sample solution is provided at 25 µL, 10mM.
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AB21 hydrochloride shows Kis of 12 nM and 14 nM with or without Phenytoin in the S1R Radioligand Binding Assay[1].
AB21 hydrochloride (20 mg/kg, s.c., administered 30 min before the injection of Capsaicin ) reverses mechanical allodyniain in Capsaicin -induced pain model, and exhibits higher potency than BD1063 dhydrochloride [1].
References:
[1]. Dichiara M, et al. Synthesis, Computational Insights, and Evaluation of Novel Sigma Receptors Ligands. ACS Chem Neurosci. 2023 May 17;14(10):1845-1858.
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