Acivicin (Synonyms: Antibiotic AT-125, NSC 163501, U 42126) |
| Katalog-Nr.GC42707 |
Acivicin (AT-125), ein von Streptomyces sviceus produziertes Naturprodukt, ist ein Inhibitor der γ-Glutamyl-Transpeptidase (GGT).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 42228-92-2
Sample solution is provided at 25 µL, 10mM.
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Acivicin is a glutamine analog that irreversibly inhibits glutamine-dependent amidotransferases involved in nucleotide and amino acid biosynthesis (Kis = 10 and 560 μM for anthranilate synthase and glutamate synthase, respectively). It also reversibly inhibits γ-glutamyl transpeptidase. Acividin has been used to elucidate aspects of glutathione metabolism and has known anti-tumorigenic activity.
Average Rating: 5 (Based on Reviews and 11 reference(s) in Google Scholar.)
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