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AM 12

Katalog-Nr.GC50475

TRPC5 inhibitor

Products are for research use only. Not for human use. We do not sell to patients.

AM 12 Chemische Struktur

Cas No.: 2387510-84-9

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10 mg
242,00 $
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50 mg
1.019,00 $
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

TRPC5 inhibitor (IC50 = 0.28 μM); Galangin derivative. Exhibits some selectivity for TRPC5 over TRPC2, 3 and 4. Inhibits effects of TRPC5 activator (-)-Englerin A, but potentiates effects of physiological activators Sphingosine-1-phosphate and LPC.

Naylor et al (2016) Natural and synthetic flavonoid modulation of TRPC5 channels. Br.J.Pharmacol. 173 562 PMID:26565375

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