Amelparib |
| Katalog-Nr.GC70420 |
Amelparib ist ein starker, oral aktiver und wasserlöslicher Inhibitor von PARP-1.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1227156-72-0
Sample solution is provided at 25 µL, 10mM.
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Amelparib is a potent, orally active, and water-soluble inhibitor of PARP-1. Amelparib inhibits PARP-1 activity (IC50 =18.5 nmol/L) and cellular PAR formation (IC50 =10.7 nmol/L) in the nanomolar range. Amelparib is a potential neuroprotective agent. Amelparib has the potential for the research of acute ischaemic stroke.
References:
[1]. Kim Y, et al. Neuroprotective effects of a novel poly (ADP-ribose) polymerase-1 inhibitor, JPI-289, in hypoxic rat cortical neurons. Clin Exp Pharmacol Physiol. 2017;44(6):671-679.
Review for Amelparib
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for Amelparib
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