Aminooxy-PEG3-propargyl |
| Katalog-Nr.GC66727 |
Aminooxy-PEG3-Propargyl ist ein PEG-basierter PROTAC-Linker, der bei der Synthese von PROTACs verwendet werden kann.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1807537-27-4
Sample solution is provided at 25 µL, 10mM.
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Aminooxy-PEG3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[1]. Christopher Semko, et al. Rapamycin analogs as mtor inhibitors. WO2018204416A1.
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