Amosulalol |
Katalog-Nr.GC70259 |
Amosulalol (YM 09538) ist ein oral aktiver und dualer Inhibitor des α1/β1-Adrenergic Receptors.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 85320-68-9
Sample solution is provided at 25 µL, 10mM.
Amosulalol (3-30 mg/kg; p.o.; single dose) reduces acute systolic blood pressure in hypertensive rats[1].
Amosulalol (50 mg/kg; p.o.; twice daily for 12 weeks) produces an intolerant antihypertensive effect and also reduces central rate and increases PRA in hypertensive rat models[1].
References:
[1]. Honda K, et al. Autonomic and antihypertensive activity of oral amosulalol (YM-09538), a combined alpha- and beta-adrenoceptor blocking agent in conscious rats. Jpn J Pharmacol. 1985 May;38(1):31-41.
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