Anrukinzumab |
| Katalog-Nr.GC72390 |
Anrukinzumab (IMA-638) ist ein humanisierter monoklonaler Antikörper gegen IL-13.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 910649-32-0
Sample solution is provided at 25 µL, 10mM.
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Anrukinzumab (IMA-638; 10 mg/kg; intravenous infusion; single) reduces lung inflammation in cynomolgus monkey model of lung inflammation[1].
References:
[1]. Bree A, et al. IL-13 blockade reduces lung inflammation after Ascaris suum challenge in cynomolgus monkeys. J Allergy Clin Immunol. 2007 May;119(5):1251-7.
[2]. Reinisch W, et al. Anrukinzumab, an anti-interleukin 13 monoclonal antibody, in active UC: efficacy and safety from a phase IIa randomised multicentre study. Gut. 2015 Jun;64(6):894-900.
[3]. Elias JA, et al. IL-13 in asthma. The successful integration of lessons from mice and humans. Am J Respir Crit Care Med. 2011 Apr 15;183(8):957-8.
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