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BC-7013

Katalog-Nr.GC70378

BC-7013 ist ein neuartiges halbsynthetisches Pleuromutilin-Derivat.

Products are for research use only. Not for human use. We do not sell to patients.

BC-7013 Chemische Struktur

Cas No.: 1028291-66-8

Größe Preis Lagerbestand Menge
1 mg
157,00 $
Auf Lager
5 mg
338,00 $
Auf Lager
10 mg
540,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
BC-7013 is a novel semi-synthetic pleuromutilin derivative. BC-7013 has excellent activity against Gram-positive pathogenic bacteria. BC-7013 exhibits potent antibacterial properties against both Staphylococcus, Streptococcus and penicillin-resistant Streptococcus pneumoniae. BC-7013 has activity against Gram-positive pathogenic bacteria, BC-7013 is useful in the research of acute bacterial skin and skin structure infection (ABSSSI).

BC-7013 shows strong inhibitory activity against 303 tested S. aureus isolates with a MIC50 value of 0.015 µg/mL[2].
BC-7013 exhibits potent activity against group A streptococci and group B streptococci with MIC90s values of 0.03 µg/mL and 0.06 µg/mL, respectively[2].

References:
[1]. Shang R, et al. Efficient antibacterial agents: a review of the synthesis, biological evaluation and mechanism of pleuromutilin derivatives. Curr Top Med Chem. 2013;13(24):3013-25.
[2]. Biedenbach D J, et al. In vitro antibacterial spectrum of BC-7013, a novel pleuromutilin derivative for topical use in humans. Interscience Conference on Antimicrobial Agents and Chemotherapy. 2009, 49: 199

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