BE-24566B (Synonyms: L-755,805) |
Katalog-Nr.GC46908 |
A fungal metabolite
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 149466-04-6
Sample solution is provided at 25 µL, 10mM.
BE-24566B is a polyketide fungal metabolite originally isolated from S. violaceusniger.1 It is active against B. subtilis, B. cereus, S. aureus, M. luteus, E. faecalis, and S. thermophilus (MICs = 1.56, 1.56, 1.56, 1.56, 3.13, and 3.13 µg/ml, respectively). BE-24566B is an endothelin (ET) receptor antagonist (IC50s = 11 and 3.9 µM for ETA and ETB receptors, respectively).2
1.Kojiri, K., Nakajima, S., Fuse, A., et al.BE-24566B, a new antibiotic produced by Streptomyces violaceusnigerJ. Antibiot. (Tokyo)48(12)1506-1508(1995) 2.Lam, Y.K.T., Hensens, O., Helms, G., et al.L-755,805, a new polyketide endothelin binding inhibitor from an actinomyceteTetrahedron Lett.36(12)2013-2016(1995)
Average Rating: 5
(Based on Reviews and 32 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *