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Biotin-C4-amide-C5-NH2

Katalog-Nr.GC65681

Biotin-C4-Amid-C5-NH2 ist ein spaltbarer ADC-Linker, der bei der Synthese von AntikÖrper-Wirkstoff-Konjugaten (ADCs) verwendet wird.

Products are for research use only. Not for human use. We do not sell to patients.

Biotin-C4-amide-C5-NH2 Chemische Struktur

Cas No.: 151294-96-1

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100mg
59,80 $
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250mg
94,50 $
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Sample solution is provided at 25 µL, 10mM.

Description of Biotin-C4-amide-C5-NH2

Biotin-C4-amide-C5-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Chemical Properties of Biotin-C4-amide-C5-NH2

Cas No. 151294-96-1 SDF
Formula C14H26N4O2S M.Wt 314.45
Löslichkeit Storage 4°C, protect from light
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Biotin-C4-amide-C5-NH2

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 3.1802 mL 15.9008 mL 31.8016 mL
5 mM 0.636 mL 3.1802 mL 6.3603 mL
10 mM 0.318 mL 1.5901 mL 3.1802 mL
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Berechnen

In vivo Formulation Calculator (Clear solution) of Biotin-C4-amide-C5-NH2

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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