Boc-NH-PEG4-CH2CH2NH2 |
Katalog-Nr.GC60656 |
Boc-NH-PEG4-CH2CH2NH2 ein spaltbarer PEG-ADC-Linker mit 5 Einheiten, der bei der Synthese von AntikÖrper-Wirkstoff-Konjugaten (ADCs) verwendet wird. Boc-NH-PEG4-CH2CH2NH2 ist ebenfalls ein PEG-basierter PROTAC-Linker, der bei der Synthese von PROTACs verwendet werden kann.
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Cas No.: 811442-84-9
Sample solution is provided at 25 µL, 10mM.
Boc-NH-PEG4-CH2CH2NH2 a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
[1]. Hans-Georg Lerchen, et al. Preparation of antibody drug conjugates of kinesin spindle protein (KSP) inhibitors with anti-TWEAKR-antibodies. WO2016207094A1.
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