C2 L-threo Ceramide (d18:1/2:0) (Synonyms: L-threo Cer(d18:1/2:0), L-threo Ceramide (d18:1/2:0), N-acetyl-L-threo-Sphingosine) |
| Katalog-Nr.GC40709 |
C2 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 143615-69-4
Sample solution is provided at 25 µL, 10mM.
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C2 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It stimulates cholesterol efflux in CHO cells expressing the human ABCA1 receptor when used at a concentration of 10 μM, however, this efflux is 50% less than that stimulated by C2 ceramide . C2 L-threo Ceramide inhibits IL-4 production by 17% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used at a concentration of 10 μM. It also induces cell cycle arrest in the G0/G1 phase and a 7-fold increase in sphingosine accumulation as well as inhibits growth of HL-60 leukemia cells.
Average Rating: 5 (Based on Reviews and 7 reference(s) in Google Scholar.)
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