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CA/MAO-B-IN-1

Katalog-Nr.GC71502

CA/MAO-B-IN-1 (Compound 78) ist ein dualer Inhibitor für Kohlenstoffanhydrasen des menschlichen Gehirns (CA) und Monoaminoxidase-B (MAO-B), mit IC50s von 8,8 bzw. 7,0 nM.

Products are for research use only. Not for human use. We do not sell to patients.

CA/MAO-B-IN-1 Chemische Struktur

Größe Preis Lagerbestand Menge
5 mg
135,00 $
Auf Lager
10 mg
216,00 $
Auf Lager
25 mg
432,00 $
Auf Lager
50 mg
684,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
CA/MAO-B-IN-1 (Compound 78) is a dual inhibitor for human brain carbonic anhydrases (CA) and Monoamine Oxidase-B (MAO-B), with IC50s of 8.8 and 7.0 nM, respectively. CA/MAO-B-IN-1 reveals a human oral absorption of 71.9% through in silico prediction.

CA/MAO-B-IN-1 (12.5-50 μM) reverts formation of ROS, exhibits neuro- and mitochondrial protective effects against Aβ1-42 oligomer-induced neurotoxicity in cells SH-SY5Y[1].

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