CAY10781 |
Katalog-Nr.GC49094 |
An NRP-1/VEGF-A interaction inhibitor
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1210360-87-4
Sample solution is provided at 25 µL, 10mM.
CAY10781 is an inhibitor of the protein-protein interaction between neuropilin-1 (NRP-1) and VEGF-A.1 It inhibits the interaction by 43% when used at a concentration of 12.5 µM. CAY10781 also inhibits VEGF-A-induced phosphorylation of VEGFR2 in catecholamine A-differentiated (CAD) cells when used at the same concentration.
1.Perez-Miller, S., Patek, M., Moutal, A., et al.In silico identification and validation of inhibitors of the interaction between neuropilin receptor 1 and SARS-CoV-2 Spike proteinbioRxiv308783(2020)
Average Rating: 5
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