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Ciraparantag acetate

Katalog-Nr.GC71531

Ciraparantag acetate ist ein Thrombin- und Faktor-Xa-Hemmer.

Products are for research use only. Not for human use. We do not sell to patients.

Ciraparantag acetate Chemische Struktur

Cas No.: 1644388-83-9

Größe Preis Lagerbestand Menge
5 mg
108,00 $
Auf Lager
10 mg
162,00 $
Auf Lager
25 mg
342,00 $
Auf Lager
50 mg
495,00 $
Auf Lager
100 mg
765,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Ciraparantag (PER977) acetate is a thrombin and factor Xa inhibitor. Ciraparantag acetate is a broad-spectrum reversal agent for anticoagulants, including low molecular weight heparins, unfractionated heparins, and some direct oral anticoagulants, but not VKAs.

References:
[1]. Das A, et al. Novel antidotes for target specific oral anticoagulants. Exp Hematol Oncol. 2015 Sep 15;4:25.
[2]. Gomez-Outes A, et al. Specific antidotes in development for reversal of novel anticoagulants: a review. Recent Pat Cardiovasc Drug Discov. 2014;9(1):2-10.
[3]. Hu TY, et al. Reversing anticoagulant effects of novel oral anticoagulants: role of ciraparantag, andexanet alfa, and idarucizumab. Vasc Health Risk Manag. 2016 Feb 17;12:35-44.
[4]. Honickel M, et al. The Reversal of Direct Oral Anticoagulants in Animal Models. Shock. 2017 Aug;48(2):144-158.

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