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cis,cis-Muconic acid

Katalog-Nr.GC60110

cis,cis-MuconsÄure, ein metabolisches Zwischenprodukt der Klebsiella-Pneumonie, kann in AdipinsÄure und TerephthalsÄure umgewandelt werden, die wichtige Monomere synthetischer Polymere sind.

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cis,cis-Muconic acid Chemische Struktur

Cas No.: 1119-72-8

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Sample solution is provided at 25 µL, 10mM.

Description of cis,cis-Muconic acid

cis,cis-Muconic acid, a metabolic intermediate of Klebsiella pneumonia, can be converted to adipic acid and terephthalic acid, which are important monomers of synthetic polymers. cis,cis-Muconic acid is also a biochemical material that can be used for the production of various plastics and polymers and is particularly gaining attention as an adipic acid precursor for the synthesis of nylon-6,6[1][2].

[1]. Jung HM, et al. Metabolic engineering of Klebsiella pneumoniae for the production of cis,cis-muconic acid. Appl Microbiol Biotechnol. 2015;99(12):5217-5225. [2]. Shin WS, et al. Characterization of a non-phosphotransferase system for cis,cis-muconic acid production in Corynebacterium glutamicum. Biochem Biophys Res Commun. 2018;499(2):279-284.

Chemical Properties of cis,cis-Muconic acid

Cas No. 1119-72-8 SDF
Canonical SMILES OC(=O)\C=C/C=C\C(O)=O
Formula C6H6O4 M.Wt 142.11
Löslichkeit DMSO : 250 mg/mL (1759.20 mM; Need ultrasonic) Storage Store at RT
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of cis,cis-Muconic acid

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 7.0368 mL 35.184 mL 70.368 mL
5 mM 1.4074 mL 7.0368 mL 14.0736 mL
10 mM 0.7037 mL 3.5184 mL 7.0368 mL
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In vivo Formulation Calculator (Clear solution) of cis,cis-Muconic acid

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 8 reference(s) in Google Scholar.)

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