Coumetarol (Dicumoxane) |
| Katalog-Nr.GC33781 |
Coumetarol (Dicumoxan) (Dicumoxan) ist ein Vitamin-K-Antagonist.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 4366-18-1
Sample solution is provided at 25 µL, 10mM.
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Coumetarol (Dicumoxane) is a vitamin K antagonist.
Coumetarol (Dicumoxane), an oral anticoagulant, is active in both models. The vitamin K antagonist Coumetarol is effective in both models after oral treatment but inhibits the thrombus formation more strongly in the arterio-venous shunt model. Treatment with the vitamin K antagonist Coumetarol in a dose of 25 mg/kg p.o. twice daily for 2 days results in a significant reduction in thrombus weight by 50% in the venous stasis model and by 75% in the arterio-venous shunt model. In both experiments the coagulation time as measured by the Thrombotest is prolonged to the same extent[1].
[1]. Vogel GM, et al. Comparison of two experimental thrombosis models in rats effects of four glycosaminoglycans. Thromb Res. 1989 Jun 1;54(5):399-410.
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