D-myo-Inositol-2,3,5-triphosphate (ammonium salt) (Synonyms: Ins(2,3,5)P3 (ammonium salt), 2,3,5IP3 (ammonium salt)) |
Katalog-Nr.GC43532 |
D-myo-Inositol-2,3,5-triphosphate (ammonium salt) (Ins(2,3,5)P3 (ammonium salt)) is a member of the inositol phosphate (InsP) family of second messengers that play a critical role in the transmission of cellular signals.
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Sample solution is provided at 25 µL, 10mM.
D-myo-Inositol-2,3,5-triphosphate (ammonium salt) (Ins(2,3,5)P3 (ammonium salt)) is a member of the inositol phosphate (InsP) family of second messengers that play a critical role in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)P3 is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium. Ins(2,3,5)P3 (ammonium salt) (tested as a racemic mixture) is 500-fold less potent than Ins(1,4,5)-P3 at initiating Ca2+ release when injected into Xenopus oocytes.
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