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Decylubiquinone

Katalog-Nr.GC40538

Decylubichinon ist ein Analogon von Ubichinon (Coenzym Q10).

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Decylubiquinone Chemische Struktur

Cas No.: 55486-00-5

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5mg
43,00 $
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10mg
82,00 $
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25mg
194,00 $
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50mg
348,00 $
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Decylubiquinone is an analog of ubiquinone . It blocks reactive oxygen species production in response to glutathione depletion and inhibits activation of the mitochondrial permeability transition. [1] Decylubiquinone inhibited opening of the mitochondrial permeability transition pore in response to calcium overload in rat liver mitochondria in different cell lines at concentrations between 50-100 µM.[2]

Reference:
[1]. Armstrong, J.S., Whiteman, M., Rose, P., et al. The Coenzyme Q10 analog decylubiquinone inhibits the redox-activated mitochondrial permeability transition: Role of mitochondrial complex III. J. Biol. Chem. 278(49), 49079-49084 (2003).
[2]. Devun, F., Walter, L., Belliere, J., et al. Ubiquinone analogs: A mitochondrial permeability transition pore-dependent pathway to selective cell death. PLoS One 5(7), (2010).

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