Desmorpholinyl Navitoclax-NH-Me (Synonyms: Desmorpholinyl ABT-263-NH-Me) |
| Katalog-Nr.GC60759 |
Desmorpholinyl Navitoclax-NH-Me ist ein Bcl-xL-Inhibitor. Desmorpholinyl Navitoclax-NH-Me und ein CRBN-Ligand fÜr die E3-Ubiquitin-Ligase kÖnnen bei der Synthese des PROTAC BCL-XL-Abbaumittels XZ739 verwendet werden.
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Cas No.: 2365172-82-1
Sample solution is provided at 25 µL, 10mM.
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Desmorpholinyl Navitoclax-NH-Me is a Bcl-xL inhibitor. Desmorpholinyl Navitoclax-NH-Me and a CRBN ligand for the E3 ubiquitin ligase can be used in the synthesis of PROTAC BCL-XL degrader XZ739 [1][2].
[1]. Guangrong Zheng, et al. Agents de dÉgradation de protÉines bcl-2 pour le traitement du cancer. WO2019144117A1.
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