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Doxofylline-d6

Katalog-Nr.GC71605

Doxofylline-d6 ist das Deuterium mit der Bezeichnung Doxofyllin.

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Doxofylline-d6 Chemische Struktur

Cas No.: 1219805-99-8

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1 mg
171,00 $
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Doxofylline-d6 is the deuterium labeled Doxofylline. Doxofylline is an antagonist of adenosine A1 receptor which also inhibits phosphodiesterase IV.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

References:
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
[2]. Shukla D, et al. Doxofylline: a promising methylxanthine derivative for the treatment of asthma and chronic obstructive pulmonary disease. Expert Opin Pharmacother. 2009 Oct;10(14):2343-56.

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