E7449 mesylate - 2X-121 |
| Katalog-Nr.GB40190 |
E7449 mesylate is a potent, brain penetrable and orally bioavailable dual inhibitor of PARP1/2 and tankyrase1/2, which inhibits growth of DNA repair deficient tumors and antagonizes Wnt signalling. E7449 mesylate exhibits IC50 values of 2.0 and 1.0 nM for PARP1 and PARP2, respectively.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1140965-47-4
Sample solution is provided at 25 µL, 10mM.
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E7449 mesylate is a potent, brain penetrable and orally bioavailable dual inhibitor of PARP1/2 and tankyrase1/2, which inhibits growth of DNA repair deficient tumors and antagonizes Wnt signalling. E7449 mesylate exhibits IC50 values of 2.0 and 1.0 nM for PARP1 and PARP2, respectively.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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