EBOV-IN-1 |
| Katalog-Nr.GC72667 |
EBOV-IN-1 (com 3.47) is an adamantane dipeptide piperazine and an inhibitor of Ebola virus (EBOV).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1335113-30-8
Sample solution is provided at 25 µL, 10mM.
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EBOV-IN-1 (com 3.47) is an adamantane dipeptide piperazine and an inhibitor of Ebola virus (EBOV). EBOV-IN-1 targets Niemann-Pick C1 (NPC1) and inhibits its binding to the EBOV glycoprotein (GP) that activates and mediates viral penetration into host cells, thereby inhibiting EBOV infection. EBOV-IN-1 inhibits pseudotyped EBOV infection with an IC50 of 13 nM.
References:
[1]. Liu H, et al. Identification of Potent Ebola Virus Entry Inhibitors with Suitable Properties for in Vivo Studies. J Med Chem. 2018 Jul 26;61(14):6293-6307.
Review for EBOV-IN-1
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for EBOV-IN-1
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