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Farnesyl Pyrophosphate ammonium

Katalog-Nr.GC70353

Farnesyl Pyrophosphate ammonium Salz, ein 15-Kohlenstoff-Isoprenoid, ist ein metabolisches Zwischenprodukt des Mevalonat-Signalweges (MVA).

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Farnesyl Pyrophosphate ammonium Chemische Struktur

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1 mg (2.31 mM * 1 mL in MeOH/NH4OH (70:30))
504,00 $
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Farnesyl Pyrophosphate ammonium salt, a 15-carbon isoprenoid, is a metabolic intermediate of the mevalonate (MVA) pathway. Farnesyl pyrophosphate ammonium salt is a TRPM2 (TRP Channel) agonist, and activates TRPM2 opening for ion influx. Farnesyl pyrophosphate ammonium salt is a key branch substrate for cholesterol synthesis, ubiquinones synthesis, protein farnesylation decoration, and geranyl-geranyl pyrophosphate (GGPP) synthesis.

References:
[1]. Jing Chen, et al. Farnesyl pyrophosphate is a new danger signal inducing acute cell death. PLoS Biol. 2021 Apr 26;19(4):e3001134.

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