Startseite>>FITC-labeled Tominersen sodium

FITC-labeled Tominersen sodium

Katalog-Nr.GC71124

FITC-labeled Tominersen sodium ist der Tominersen mit FITC gekennzeichnet.

Products are for research use only. Not for human use. We do not sell to patients.

FITC-labeled Tominersen sodium Chemische Struktur

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1mg
246,00 $
Auf Lager
5mg
475,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.

Description of FITC-labeled Tominersen sodium

FITC-labeled Tominersen (sodium) is the Tominersen labeled with FITC. Tominersen (RG6042) is a second-generation 2′-O-(2-methoxyethyl) antisense oligonucleotide that targets huntingtin protein (HTT) mRNA and potently suppresses HTT production. Tominersen improves survival and reduces brain atrophy in mice. Tominersen can be used for the research of Huntington’s disease (HD).

Chemical Properties of FITC-labeled Tominersen sodium

Cas No. SDF
Formula M.Wt 7654
Löslichkeit H2O : ≥ 100 mg/mL (13.07 mM) Storage -20°C, sealed storage, away from moisture and light
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of FITC-labeled Tominersen sodium

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 0.1307 mL 0.6533 mL 1.3065 mL
5 mM 0.0261 mL 0.1307 mL 0.2613 mL
10 mM 0.0131 mL 0.0653 mL 0.1307 mL
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Berechnen

In vivo Formulation Calculator (Clear solution) of FITC-labeled Tominersen sodium

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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