Fmoc-Gly-Gly-D-Phe-OtBu |
Katalog-Nr.GC38913 |
Fmoc-Gly-Gly-D-Phe-OtBu ist ein spaltbarer ADC-Linker, der bei der Synthese von AntikÖrper-Wirkstoff-Konjugaten (ADCs) verwendet wird. Fmoc-Gly-Gly-D-Phe-OtBu ist das R-Isomer von Fmoc-Gly-Gly-Phe-OtBu.
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Sample solution is provided at 25 µL, 10mM.
Fmoc-Gly-Gly-D-Phe-OtBu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Gly-Gly-D-Phe-OtBu is the R-isomer of Fmoc-Gly-Gly-Phe-OtBu [1].
[1]. Bak A, et al. Synthesis and evaluation of the physicochemical properties of esterase-sensitive cyclic prodrugs of opioid peptides using an (acyloxy)alkoxy linker. J Pept Res. 1999 Apr;53(4):393-402.
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