Fodipir (DPDP) |
| Katalog-Nr.GC31992 |
Fodipir (DPDP) ist ein aktiver Metabolit von Mangafodipir, der an der Mangafodipir-vermittelten Zytoprotektion gegen &77#946;-Hydroxycholesterin-induzierten Zelltod beteiligt ist.
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Cas No.: 118248-91-2
Sample solution is provided at 25 µL, 10mM.
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Fodipir is an active metabolite of mangafodipir, involved in mangafodipir-mediated cytoprotection against 7β-hydroxycholesterol-induced cell death.
Fodipir is an active metabolite of mangafodipir, involved in mangafodipir-mediated cytoprotection against 7β-hydroxycholesterol-induced cell death. Fodipir (Dp-dp; Dipyridoxyl diphosphate; 100 μM) shows the best cytopretective effect on 7β-OH-mediated cell death after treatment for 8 h. Fodipir also reduces 7β-OH-induced cellular ROS production and lysosomal membrane permeabilization (LMP)[1].
[1]. Laskar A, et al. Fodipir and its dephosphorylated derivative dipyridoxyl ethyldiamine are involved in mangafodipir-mediated cytoprotection against 7β-hydroxycholesterol-induced cell death. Pharmacology. 2013;92(3-4):182-6.
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