FPI-1523 sodium |
| Katalog-Nr.GC70836 |
FPI-1523 sodium, ein Derivat von Avibactam, ist ein potenter β-Lactamasehemmer mit Kds von 4 nM und 34 nM für CTX-M-15 bzw. OXA-48.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1452459-52-7
Sample solution is provided at 25 µL, 10mM.
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FPI-1523 sodium inhibits K12 E. coli K12 and PBP2, with MIC and IC50 of 4 μg/mL and 0.4 μg/mL, respectively[1].
FPI-1523 sodium inhibit E. coli BW25113 pGDP-2 transformants either with an empty vector or expressing different β-lactamases, with low MICs (1-2 μM)[1].
References:
[1]. King AM, et, al. Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-β-Lactamases and Penicillin-Binding Proteins. ACS Chem Biol. 2016 Apr 15;11(4):864-8.
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