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Pyr-Arg-Thr-Lys-Arg-AMC

Katalog-Nr.GA23423

The fluorogenic substrate pERTKR-AMC is efficiently cleaved by furin, a mammalian homolog of the yeast Kex2 endoprotease (kcat/Km approx. 2.10? M-¹s-¹). As a calcium-dependent serine protease associated with Golgi membranes, furin is responsible for the secretory processing of precursor proteins at paired basic residues. Also cleaved by proprotein convertase 4. Pyr-RTKR-AMC is an excellent substrate for flavivirin.

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Pyr-Arg-Thr-Lys-Arg-AMC Chemische Struktur

Cas No.: 155575-02-3

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5mg
143,00 $
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25mg
572,00 $
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Sample solution is provided at 25 µL, 10mM.

Product has been cited by 1 publications

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The fluorogenic substrate pERTKR-AMC is efficiently cleaved by furin, a mammalian homolog of the yeast Kex2 endoprotease (kcat/Km approx. 2.10 M-¹s-¹). As a calcium-dependent serine protease associated with Golgi membranes, furin is responsib

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