Eprodisate |
| Katalog-Nr.GC35999 |
Eprodisate ist eine neue Verbindung, die entwickelt wurde, um die Wechselwirkungen zwischen amyloidogenen Proteinen und Glykosaminoglykanen zu stÖren und dadurch die Polymerisation von Amyloidfibrillen und die Ablagerung der Fibrillen in Geweben zu hemmen.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 21668-77-9
Sample solution is provided at 25 µL, 10mM.
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Eprodisate is a new compound designed to interfere with interactions between amyloidogenic proteins and glycosaminoglycans and thereby inhibit polymerization of amyloid fibrils and deposition of the fibrils in tissues[1]. Eprodisate slow the progression of AA amyloidosis-related renal disease and has possible applicability to other types of amyloidosis[2].
[1]. Dember LM, et al. Eprodisate for the treatment of renal disease in AA amyloidosis. N Engl J Med. 2007 Jun 7;356(23):2349-60. [2]. Manenti L, et al. Eprodisate in amyloid A amyloidosis: a novel therapeutic approach• Expert Opin Pharmacother. 2008 Aug;9(12):2175-80.
Average Rating: 5 (Based on Reviews and 17 reference(s) in Google Scholar.)
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