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GB-110

Katalog-Nr.GC36125

GB-110 ist ein potenter, oral aktiver und nichtpeptidischer Agonist des Protease-aktivierten Rezeptors 2 (PAR2).

Products are for research use only. Not for human use. We do not sell to patients.

GB-110 Chemische Struktur

Cas No.: 1252806-70-4

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

GB-110 is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist. GB-110 selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM[1]. Protease activated receptor 2[1]

[1]. Barry GD, et al. Novel agonists and antagonists for human protease activated receptor 2. J Med Chem. 2010 Oct 28;53(20):7428-40.

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