JNJ-37822681 dihydrochloride |
| Katalog-Nr.GC36370 |
JNJ-37822681-Dihydrochlorid ist ein potenter, spezifischer, zentral aktiver, schnell dissoziierender Dopamin-D2-Rezeptorantagonist mit einer mÄßigen BindungsaffinitÄt fÜr den Dopamin-D2L-Rezeptor (Ki = 158 nM), der Potenzial fÜr die Behandlung von Schizophrenie und bipolaren StÖrungen hat[1 ].
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2108806-02-4
Sample solution is provided at 25 µL, 10mM.
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JNJ-37822681 dihydrochloride is a potent, specific, centrally active, fast-dissociating dopamine D2 receptor antagonist with a moderate binding affinity for the dopamine D2L receptor (Ki =158 nM), which has potential for the treatment of schizophrenia and bipolar disorder[1]. Ki: 158 nM (dopamine D(2))[1]
[1]. Langlois X, et al. Pharmacology of JNJ-37822681, a specific and fast-dissociating D2 antagonist for the treatment of schizophrenia. J Pharmacol Exp Ther. 2012 Jul;342(1):91-105.
Average Rating: 5 (Based on Reviews and 9 reference(s) in Google Scholar.)
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