MMSET-IN-1 |
Katalog-Nr.GC36636 |
MMSET-IN-1 ist ein Inhibitor der SET-DomÄne des multiplen Myeloms (MMSET, auch bekannt als NSD2/WHSC1) gegen SETD2 und MMSET mit IC50-Werten von 0,49 bzw. 3,3 μM. MMSET-IN-1 hat einen Kd von 1,6 μM fÜr MMSET.
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Cas No.: 1998139-29-9
Sample solution is provided at 25 µL, 10mM.
MMSET-IN-1 is a multiple myeloma SET domain (MMSET, aka NSD2/WHSC1) inhibitor against SETD2 and MMSET with IC50s of 0.49 and 3.3 μM, respectively. MMSET-IN-1 has a Kd of 1.6 μM for MMSET[1]. IC50: 0.49 μM (SETD2), 3.3 μM (MMSET)[1]Kd: 1.6 μM[1]
[1]. Tisi D, et al. Structure of the Epigenetic Oncogene MMSET and Inhibition by N-Alkyl Sinefungin Derivatives. ACS Chem Biol. 2016 Nov 18;11(11):3093-3105.
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