PTD-p65-P1 Peptide |
Katalog-Nr.GC37036 |
PTD-p65-P1-Peptid ist ein potenter, selektiver nukleÄrer Transkriptionsfaktor-NF-κB-Inhibitor und stammt von der p65-Untereinheit der NF-κB-AminosÄurereste 271-282, die selektiv die NF-κB-Aktivierung hemmt, die durch verschiedene entzÜndliche Stimulation, Down- regulieren die NF-κB-vermittelte Genexpression und regulieren die Apoptose hoch.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
PTD-p65-P1 Peptide is a nuclear transcription factor NF-kappaB inhibitor, composed of a membrane-translocating peptide sequence generated from antennapedia (PTD) conjugated with p65-P1, which selectively inhibits activation induced by various inflammatory stimuli[1]. NF-kappaB[1]
[1]. Takada Y, et al. Identification of a p65 peptide that selectively inhibits NF-kappa B activation induced by various inflammatory stimuli and its role in down-regulation of NF-kappaB-mediated gene expression and up-regulation of apoptosis. J Biol Chem. 2004 Apr 9;279(15):15096-104.
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