TAS4464 hydrochloride |
Katalog-Nr.GC37743 |
TAS4464 (Hydrochlorid) ist ein hochwirksamer und selektiver Inhibitor des NEDD8-aktivierenden Enzyms (NAE) mit einem IC50 von 0,955 nM.
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Cas No.: 1848959-11-4
Sample solution is provided at 25 µL, 10mM.
TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM[1]. IC50:0.955 nM (NAE)[1]
[1]. Yoshimura C, et al. TAS4464, a highly potent and selective inhibitor of NEDD8 activating enzyme, suppresses neddylation and shows antitumor activity in diverse cancer models. Mol Cancer Ther. 2019 May 15.
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