Teneligliptin hydrobromide hydrate |
Katalog-Nr.GC37757 |
Teneligliptin-Hydrobromid-Hydrat ist ein potenter Chemotyp-DPP-4-Inhibitor auf Prolylthiazolidin-Basis, der humanes Plasma, Rattenplasma und humanes rekombinantes DPP-4 in vitro kompetitiv hemmt, mit IC50-Werten von etwa 1 nM.
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Cas No.: 1572583-29-9
Sample solution is provided at 25 µL, 10mM.
Teneligliptin hydrobromide hydrate is a potent chemotype prolylthiazolidine-based DPP-4 inhibitor, which competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50s of approximately 1 nM[1].
[1]. Fukuda-Tsuru S, et al. A novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor, teneligliptin, improves postprandial hyperglycemia and dyslipidemia after single and repeated administrations. Eur J Pharmacol. 2012 Dec 5;696(1-3):194-202.
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