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Zaurategrast ethyl ester

Katalog-Nr.GC37961

Zaurategrast-Ethylester (CDP323), das Ethylester-Prodrug von CT7758, ist ein α4β1/α4β7-Integrin-Antagonist, der zur Behandlung von EntzÜndungs- und Autoimmunerkrankungen eingesetzt wird.

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Zaurategrast ethyl ester Chemische Struktur

Cas No.: 455264-30-9

Größe Preis Lagerbestand Menge
10mM (in 1mL DMSO)
436,00 $
Auf Lager
10mM (in 1mL DMSO)
436,00 $
Auf Lager
5mg
360,00 $
Auf Lager
10mg
621,00 $
Auf Lager
25mg
1.125,00 $
Auf Lager
50mg
1.800,00 $
Auf Lager
100mg
2.880,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Zaurategrast ethyl ester (CDP323), the ethyl ester prodrug of CT7758[1], is a α4β1/α4β7 integrin antagonist used for the treatment of inflammatory and autoimmune disorders[2]. α4β1/α4β7 integrin[1]

Zaurategrast ethyl ester (CDP323), an ethyl ester prodrug of CT7758, shows some improvements in increasing mass transfer[1].

[1]. Chanteux H, et al. Cross-Species Differences in the Preclinical Pharmacokinetics of CT7758, an α4β1/α4β7 Integrin Antagonist. Drug Metab Dispos. 2015 Sep;43(9):1381-91. [2]. Davenport RJ, et al. Alpha4-integrin antagonism--an effective approach for the treatment of inflammatory diseases• Drug Discov Today. 2007 Jul;12(13-14):569-76.

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