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Phenazepam-d4 (CRM) (Synonyms: Fenazepam-d4)

Katalog-Nr.GC45546

 

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Phenazepam-d4 (CRM) Chemische Struktur

Cas No.: 1184980-42-4

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Sample solution is provided at 25 µL, 10mM.

Description of Phenazepam-d4 (CRM)

Phenazepam-d4 (CRM) is certified reference material intended for use as an internal standard for the quantification of phenazepam by GC- or LC-mass spectrometry. Phenazepam is categorized as a benzodiazepine.1 It has sedative and hypnotic properties and has been detected in illicit tablets.2 This product is intended for research and forensic applications.

References
1. Kalinina, T.S., Garibova, T.L., and Voronina, T.A. Descriminative effects of phenazepam and gidazepam in rats: Comparison with other GABA-related drugs. Pharmacol. Biochem. Behav. 64(2), 397-401 (1999).
2. Oyemade, A. New uncontrolled benzodiazepine, phenazepam, emerging drug of abuse. Innov. Clin. Neurosci. 9(9), 10-13 (2012).

Chemical Properties of Phenazepam-d4 (CRM)

Cas No. 1184980-42-4 SDF
Überlieferungen Fenazepam-d4
Canonical SMILES BrC1=CC2=C(N([H])C(CN=C2C3=C([2H])C([2H])=C([2H])C([2H])=C3Cl)=O)C=C1
Formula C15H6BrClD4N2O M.Wt 353.6
Löslichkeit Soluble in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Phenazepam-d4 (CRM)

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.8281 mL 14.1403 mL 28.2805 mL
5 mM 0.5656 mL 2.8281 mL 5.6561 mL
10 mM 0.2828 mL 1.414 mL 2.8281 mL
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In vivo Formulation Calculator (Clear solution) of Phenazepam-d4 (CRM)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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