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Guandine thiocyanate

Katalog-Nr.GD13917

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Guandine thiocyanate Chemische Struktur

Cas No.: 593-84-0

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500g
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products
Guanidine thiocyanate is a strong protein denaturant and potent inhibitor of nucleases. Guanidinium thiocyanate is a nucleic acid protector in the extraction of DNA and RNA from cells. Guanidine thiocyanate is a common component of buffers used for nucleic acid extraction.

Guanidine thiocyanate based-nucleic acid extraction buffers can effectively inactivate high-consequence enveloped viruses, such as Ebola virus, Marburg virus, and Rift Valley Fever virus, as well as West Nile virus, influenza, Venezuelan equine encephalitis virus, and recently, SARS-CoV-2[1].
Guanidine thiocyanate-based nucleic acid extraction buffers are an effective means of inactivating poliovirus infectious materials and potentially infectious materials[1].

[1]. Michelle J Honeywood, et al. Use of guanidine thiocyanate-based nucleic acid extraction buffers to inactivate poliovirus in potentially infectious materials. J Virol Methods. 2021 Nov:297:114262.  

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