Gemcitabine monophosphate (sodium salt hydrate) |
| Katalog-Nr.GC43741 |
Gemcitabine monophosphate is a monophosphate form of the deoxycytidine analog gemcitabine.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Gemcitabine monophosphate is a monophosphate form of the deoxycytidine analog gemcitabine . It has synergistic effects when used in nanoparticle form in combination with cisplatin nanoparticles in vitro at a one-to-one molar ratio (IC50s = 5.95, 34.8, and 15.7 µM for nanoparticle combination, gemcitabine monophosphate alone, and cisplatin alone, respectively). In a stroma-rich mouse xenograft model, the nanoparticle combination of gemcitabine and cisplatin inhibits tumor growth and increases apoptosis.
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